Determinants of quality of life after epilepsy surgery: Systematic review and evidence summary

► More than 90% of studies demonstrate a positive impact of epilepsy surgery on health-related quality of life. ► Preoperative psychological status and patients' expectations affect health-related quality of life after surgery. ► Seizure freedom, but not seizure improvement, relates to better health-related quality of life after surgery. ► The methods and instruments used to assess health-related quality of life impact the results.