کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6014914 1185942 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Characterizing sleep disorders of adults with tuberous sclerosis complex: A questionnaire-based study and review
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Characterizing sleep disorders of adults with tuberous sclerosis complex: A questionnaire-based study and review
چکیده انگلیسی

An adult cohort with tuberous sclerosis complex was investigated for the prevalence of sleep disturbances and the relationship with seizure variables, medication, and psychological functioning. Information on 35 adults was gathered using four questionnaires: Epworth Sleepiness Scale (ESS), Sleep and Epilepsy Questionnaire (SEQ), Sleep Diagnosis List (SDL), and Adult Self-Report Scale (ASR). In addition, clinical, genetic and electrophysiological data were collected. Of 35 respondents, 25 had a history of epilepsy. A subjective sleep disorder was found in 31% of the cohort. Insomnia scores showed a significant positive correlation with obstructive sleep apnea syndrome and restless legs syndrome scores. Significant correlations were found between daytime sleepiness and scores on depression, antisocial behavior, and use of mental health medication. A subgroup using antiepileptic medication showed high correlations between daytime sleepiness, attention deficits, and anxiety scores.

Research Highlights► This was the first study to investigate sleep in adult patients with TSC. ► Results show a high prevalence of subjective sleep disorders and daytime sleepiness. ► The number of seizure types had a significant effect on insomnia. ► Daytime sleepiness correlated with higher scores on depression and antisocial behavior. ► Use of anti-epileptic drugs was correlated with sleepiness, attention deficits and anxiety.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy & Behavior - Volume 20, Issue 1, January 2011, Pages 68-74
نویسندگان
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