کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6019551 1186582 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Apoptosis of primary sensory neurons in GD1b-induced sensory ataxic neuropathy
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Apoptosis of primary sensory neurons in GD1b-induced sensory ataxic neuropathy
چکیده انگلیسی
Experimental autoimmune sensory ataxic neuropathy was induced in three of six rabbits sensitized with GD1b ganglioside (GD1b-SAN). TUNEL assay was performed on sections of dorsal root ganglia in the cauda equina. The results showed the presence of TUNEL-positive neurons in all three rabbits affected with GD1b-SAN. In contrast, no such neurons were observed in any of the sections from the unaffected rabbits that had been inoculated with GD1b, rabbits inoculated with adjuvant alone or those without inoculation. These data support that an apoptotic mechanism is involved in the pathogenesis of GD1b-SAN.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Neurology - Volume 209, Issue 1, January 2008, Pages 279-283
نویسندگان
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