کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6028901 1580922 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Relation between variants in the neurotrophin receptor gene, NTRK3, and white matter integrity in healthy young adults
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
Relation between variants in the neurotrophin receptor gene, NTRK3, and white matter integrity in healthy young adults
چکیده انگلیسی
FA was optimally predicted (based on the highest false discovery rate critical p), by five SNPs (rs1017412, rs2114252, rs16941261, rs3784406, and rs7176429; overall FDR critical p = 0.028). Gene effects were widespread and included the corpus callosum genu and inferior longitudinal fasciculus - regions implicated in several neuropsychiatric disorders and previously associated with other neurotrophin-related genetic variants in an overlapping sample of subjects. NTRK3 genetic variants, and neurotrophins more generally, may influence white matter integrity in brain regions implicated in neuropsychiatric disorders.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 82, 15 November 2013, Pages 146-153
نویسندگان
, , , , , , , , , , , , ,