Demineralised human dentine matrix stimulates the expression of VEGF and accelerates the bone repair in tooth sockets of rats

Our results showed that DHDM increases the expression of VEGF and accelerates the healing process in rats tooth sockets, by stimulating bone deposition and also vessels formation. These results suggest that DHDM has osteoinductive/osteoconductive potential and may represent an efficient grafting material on guided bone regeneration.