کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6060582 | 1200233 | 2014 | 7 صفحه PDF | دانلود رایگان |
- Whether sleep duration related to the risk of future dyslipidemia is not fully understood.
- Longer sleep duration decreased risk of future low high-density lipoprotein cholesterol.
- Longer sleep duration decreased risk of future high triglycerides.
BackgroundAlthough short sleep duration has been reported to be associated with future cardiometabolic diseases, it is not fully understood whether sleep duration is prospectively associated with the risk of each lipid profile abnormality.MethodsSubjects were nondiabetic Japanese, 40-55 years of age, who were not taking oral lipid-lowering medications: for the incidence of low high-density lipoprotein cholesterol (HDL-C), 7627 men with an HDL-C level â¥40âmg/dL; for high triglycerides, 6973 men with a triglyceride level <200âmg/dL; for high low-density lipoprotein cholesterol (LDL-C), 7273 men with an LDL-C level <160âmg/dL; for high non-HDL-C, 7415 men with a non-HDL-C level <190âmg/dL; and for high total cholesterol (TC), 7196 men with a TC level <240âmg/dL. Lipid profile abnormalities were defined according to the Adult Treatment Panel III guidelines of the National Cholesterol Education Program.ResultsDuring the 6-year observation period, there were 1022 cases of low HDL-C. Multiple-adjusted hazard ratios for low HDL-C were 0.79 (95% confidence interval, 0.64-0.97) for sleep durations of 5 to <7âh and 0.62 (0.46-0.83) for â¥7âh compared with <5âh. There were 1473 cases of high triglycerides. Multiple-adjusted hazard ratios for high triglycerides were 0.81 (0.68-0.98) for sleep durations of 5 to <7âh and 0.90 (0.72-1.13) for â¥7âh compared with <5âh. However, no association between sleep duration and the risk of future high LDL-C, non-HDL-C, or TC was observed.ConclusionsModerate and/or long sleep durations decreased the risk of future low HDL-C and high triglycerides.
Journal: Sleep Medicine - Volume 15, Issue 11, November 2014, Pages 1379-1385