کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6061537 | 1200304 | 2010 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Advances in pediatric restless legs syndrome: Iron, genetics, diagnosis and treatment
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کلمات کلیدی
Periodic limb movement disorder - اختلال حرکتی اندام دوره ایAttention-Deficit/Hyperactivity Disorder - اختلال نقص توجه / بیش فعالیPeriodic limb movements in sleep - حرکات اندام دوره ای در خوابTreatment - درمانrestless legs syndrome - سندرم پای بی قرارFerritin - فریتینGenetics - ژنتیکChildren - کودکان
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A substantial literature characterizes pediatric restless legs syndrome (RLS), which occurs in about 1.9% of individuals between 8 and 18Â years of age. Diagnostic interview techniques and an updated inventory of pediatric RLS mimics are presented. Evidence for comorbidity of pediatric RLS with attention-deficit/hyperactivity disorder, depression, and anxiety is reviewed as is the relationship to periodic limb movements in sleep and periodic limb movement disorder. The role of relative iron deficiency in pediatric RLS is discussed, along with new data indicating the benefit of iron therapy in reducing symptoms. Five genetic variants have been linked to RLS, an important finding in a condition that is highly familial in early-onset cases. Numerous case reports and case series indicate benefit for moderate to severe pediatric RLS with medication. However, to date, there have been no double-blind, placebo-controlled studies of therapy for pediatric RLS published. These and other recent advances relevant to pediatric RLS research are reviewed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sleep Medicine - Volume 11, Issue 7, August 2010, Pages 643-651
Journal: Sleep Medicine - Volume 11, Issue 7, August 2010, Pages 643-651
نویسندگان
Matthew A. Picchietti, Daniel L. Picchietti,