کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6089812 1589673 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Applied nutritional investigationPaper-filtered coffee increases cholesterol and inflammation biomarkers independent of roasting degree: A clinical trial
ترجمه فارسی عنوان
بررسی های تغذیه ای کاربردی قهوه فیلتر شده، کلسترول و بیومارکرهای التهابی را مستقیما از درجه حرارت کوره افزایش می دهد: یک کارآزمایی بالینی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
چکیده انگلیسی

ObjectiveThe aim of this study was to compare the effects of medium light roast (MLR) and medium roast (MR) paper-filtered coffee on cardiovascular risk factors in healthy volunteers.MethodsThis randomized crossover trial compared the effects of consuming three or four cups (150 mL) of MLR or MR coffee per day for 4 wk in 20 healthy volunteers. Plasma lipids, lipoprotein(a) (Lp[a]), total homocysteine, and endothelial dysfunction-related inflammation biomarkers, serum glycemic biomarkers, and blood pressure were measured at baseline and after each intervention.ResultsBoth roasts increased plasma total cholesterol, low-density lipoprotein-cholesterol, and soluble vascular cell adhesion molecule-1 (sVCAM-1) concentrations (10%, 12%, and 18% for MLR; 12%, 14%, and 14% for MR, respectively) (P < 0.05). MR also increased high-density lipoportein-cholesterol concentration by 7% (P = 0.003). Plasma fibrinogen concentration increased 8% after MR intake (P = 0.01), and soluble E-selectin increased 12% after MLR intake (P = 0.02). No changes were observed for Lp(a), total homocysteine, glycemic biomarkers, and blood pressure.ConclusionModerate paper-filtered coffee consumption may have an undesirable effect on plasma cholesterol and inflammation biomarkers in healthy individuals regardless of its antioxidant content.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nutrition - Volume 29, Issues 7–8, July–August 2013, Pages 977-981
نویسندگان
, , , , , , ,