IL-17 and neutrophils: unexpected players in the type 2 immune response

- Type 2 cytokines protect against helminths but also cause allergic disease.
- IL-17 and neutrophils unexpectedly contribute to type 2 immunity.
- IL-17 and type 2 cytokines can enhance or counter-regulate each other.
- Chitinase like proteins bridge IL-17 and type 2 responses.
- Dysregulation of the IL-17/type2 balance may cause pathology.