کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6116938 1591548 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Control of memory B cell responses by extrinsic and intrinsic mechanisms
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Control of memory B cell responses by extrinsic and intrinsic mechanisms
چکیده انگلیسی


- Secondary antibody responses by memory B cells are key to protective immunity.
- The memory B cell compartment consists of distinct subpopulations.
- B cell-intrinsic and -extrinsic mechanisms control recall responses.
- ITT phosphorylation of surface IgG is a signal signature of memory B cells.

Following primary activation, B lymphocytes generate a long-lived memory compartment to harness the organism for future reinfections by the same pathogen species. Only recently the composition and signaling signature of the scarce memory B cell pool could be explored in more detail. This review highlights current concepts of how B cells preserve their antigen experience at the cellular and molecular level.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunology Letters - Volume 178, October 2016, Pages 27-30
نویسندگان
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