The complexity of Sjögren's syndrome: Novel aspects on pathogenesis

► Etiology and many aspects of the pathogenesis of Sjögren's syndrome are still elusive. ► Today's therapies rely merely on relieving the symptoms. ► No single symptom for diagnosis of Sjögren's syndrome. ► The symptoms occur long after the onset of the disease. ► Biggest challenge remains to improve therapy and diagnosis of Sjögren's syndrome.