Intrinsic unresponsiveness of Mertk−/− B cells to chronic graft-versus-host disease is associated with unmodulated CD1d expression

► Mertk-KO B cells displayed decreased signals induced by MHC-II cross-linking. ► B cells from Mertk deficient mice were intrinsically unresponsive in chronic GVH. ► Mertk-KO MZB cells have impaired CD1d down-regulation.