Autoreactive HSP60 epitope-specific T-cells in early human atherosclerotic lesions

► First analysis of T-cells derived from early human atherosclerotic lesions. ► Proof that HSP60 reactive T-cells precede anti-HSP60 antibodies in atherogenesis. ► Identification of potentially atherogenic HSP60 peptides in human atherosclerosis. ► Interesting future diagnostic and therapeutic potential. ► Support of the “Autoimmune Concept of Atherogenesis”.