Long-term effect of mass chemotherapy, transmission and risk factors for Schistosoma mansoni infection in very low endemic communities of Venezuela

- Single dose mass chemotherapy can control S. mansoni in certain settings.
- Limited snail control may help boosting mass chemotherapy.
- Persistence of low active transmission of S. mansoni in treated communities.
- Transmission is associated with specific water site contacts and occupation (farmer).
- Farmers should have priority treatment because of their higher risk of infection.