Molecular cloning and characterization of Brugia malayi thymidylate kinase

Nucleoside analogues 5-bromo-2′-deoxyuridine (5-BrdU), 5-chloro-2′-deoxyuridine (5-CldU) and 3′-azido-3′-deoxythymidine (AZT) inhibits Brugia malayi thymidylate kinase (BmTMK) selectively as compared to human thymidylate kinase (HsTMK).