Field assessment of Trypanosoma cruzi infection and host survival in the native rodent Octodon degus

► Trypanosoma cruzi-infection in the endemic rodent Octodon degus can reach up to 70%. ► T. cruzi-infection does not affect the survivorship and body condition of O. degus. ► O. degus can be considered an asymptomatic and competent reservoir of T. cruzi.