کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6128948 1222144 2016 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prevalence and molecular characteristics of urinary and intestinal microsporidia infections in renal transplant recipients
ترجمه فارسی عنوان
فراوانی و ویژگی های مولکولی عفونت های میکروسپوریدیای ادرار و روده در گیرنده های پیوند کلیه
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
چکیده انگلیسی
Transplant recipients have been identified as a new risk group for microsporidia infection. We characterize for the first time the prevalence of microsporidia in intestinal and urinary tracts of renal transplant recipients. Molecular examination of 86 patients showed that 25.5% of them were infected; 86% were confirmed to have pathogens in their urine and 45.5% in stool. Among positive patients, 32% had microsporidia confirmed in both urine and stool. Genotyping revealed Encephalitozoon cuniculi (59%) and Enterocytozoon bieneusi (23%) monoinfections as well as coinfections with both species (18%). Moreover, we found diarrhoea and fever as symptoms significantly associated with microsporidia presence. Our results indicate that microsporidial infection should be considered in the assessment of renal transplant recipients, especially in the urinary tract, even if asymptomatic. Molecular identification of microsporidia species is relevant because of their different susceptibility for treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Microbiology and Infection - Volume 22, Issue 5, May 2016, Pages 462.e5-462.e9
نویسندگان
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