Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals

► We performed a meta-analysis on weight gain effect of Lactobacillus probiotics. ► Comparative animal and human studies were included. ► Specific Lactobacillus species were associated with a weight gain effect. ► Other specific species showed a protective effect against obesity. ► Lactobacillus probiotics impact weight regulation with a species-specific pattern.