Echinococcus granulosus tegumental enzymes as in vitro markers of pharmacological damage: A biochemical and molecular approach

► Chemotherapeutic treatment of cystic echinococcosis remains unsolved. ► We develop an easy method for in vitro drug screening in Echinococcus granulosus. ► Measurement of AP, AChE and GGT provided evidence of drug effects. ► We demonstrated the gene expression of these transmembrane enzymes. ► GGT is proposed as the ideal viability marker during in vitro pharmacological studies.