Optimization and comparison of balloon-based partial breast brachytherapy using a single source, a standard plan line source, and both forward and inverse planned multilumen techniques

Multiple sources in a single catheter improve coverage at catheter ends, whereas ML can further improve coverage and reduce dose to organs at risk. Using a standard line source as a starting point for forward planning ML means increase in planning time is kept to a minimum, making it a practicable option for centers without inverse planning software. Patients previously ineligible for treatment with a single catheter may be treated using ML.