کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6243806 | 1609786 | 2012 | 7 صفحه PDF | دانلود رایگان |
ObjectiveThe purpose of our study was to evaluate the value of chemical shift imaging (CSI) and diffusion weighted imaging (DWI) at 3.0 T MRI in adrenal hyperattenuating lesions.MethodsFifty-one hyperattenuating adrenal lesions in 40 patients were evaluated. Signal intensity index (SII), adrenal to spleen ratio (ASR) and apparent diffusion coefficient (ADC) were used as quantitative analysis parameters.ResultsThe mean SII, ASR and ADC values were: benign pheochromocytomas (n = 22), 7.04%; 0.96, 1.15 Ã 10â3 mm2/s; lipid-poor adenomas (n = 18), 33.77%, 0.71, 1.07 Ã 10â3 mm2/s; malignant tumors (n = 7), 11.24%; 1.00; 0.92 Ã 10â3mm2/s. There were significant differences between the lipid-poor adenomas and nonadenomas for SII and ASR, and there were significant differences between the benign and the malignant tumor ADC values. The optimal diagnostic threshold point of SII and ASR for lipid-poor adenomas was 11.96%, 0.83, the sensitivity and specificity were 88.9%, 97.5% and 97%, 83.3%. The optimal diagnostic threshold point of ADC value for benign lesions and malignant tumors was 1.04 Ã 10â3 mm2/s, the sensitivity and specificity were 61.4% and 85.7%.ConclusionQuantitative analysis of chemical shift MRI and DWI can help to characterize the hyperattenuating adrenal lesions, especially in differentiatiation between the lipid-poor adenomas, the benign pheochromocytomas, and the malignant tumors.
Journal: European Journal of Radiology - Volume 81, Issue 9, September 2012, Pages 2137-2143