Contribution of regional 3D meniscus and cartilage morphometry by MRI to joint space width in fixed flexion knee radiography-A between-knee comparison in subjects with unilateral joint space narrowing

3D measures of meniscus and cartilage provide significant, independent information in explaining side-differences in radiographic JSW in fixed flexion radiographs. Tibial coverage by the meniscus and central femoral cartilage explained two thirds of the variability in minimum and fixed location JSW. JSW provides a better representation of (central) femorotibial cartilage thickness, when optimal positioning of the fixed flexion radiographs is achieved.