NR2A subunit of the N-methyl d-aspartate receptors are required for potentiation at the mossy fiber to granule cell synapse and vestibulo-cerebellar motor learning

▶Plasticity in the cerebellar granular layer contributes to cerebellar motor learning. ▶NR2A is necessary for the induction of LTP at the mossy fiber to granule cell. ▶NR2A activation does not affect general eye movement performance. ▶NR2A activation is essential for cerebellar dependent learning.