Caspase-3 is a target gene of c-Jun:ATF2 heterodimers during apoptosis induced by activity deprivation in cerebellar granule neurons

► Caspase-3 is up-regulated during apoptosis induced by activity deprivation in CGNs. ► Caspase-3 is a target gene of the JNK/c-Jun:ATF2 pathway. ► c-Jun:ATF2 heterodimers bind directly to the ATF site of the caspase-3 promoter in vivo.