کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6308091 | 1618847 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China Evaluation of the in vitro estrogenicity of emerging bisphenol analogs and their respective estrogenic contributions in municipal sewage sludge in China](/preview/png/6308091.png)
چکیده انگلیسی
There is a potential risk to the environment from persistent estrogenic compounds in sewage sludge. In this study, eight bisphenols (BPs) were identified in sewage sludge collected from wastewater treatment plants in 15 cities in China. The estrogenic potencies of the eight BPs and the estrogenic activities of sludge samples were evaluated using a bioluminescence yeast estrogen screen (BLYES) assay. All sludge samples elicited considerable estrogenic activity at a range of 2.8-4.7Â ng E2Â gâ1 dry weight (dw). All BPs exhibited estrogenic activity in the BLYES assay, but there were significant differences between the potency of individual chemicals. Bisphenol AF had the highest activity, followed by tetrachlorobisphenol A, bisphenol F, bisphenol A, bisphenol E, bisphenol S and 2,4-dihydroxybenzophenone. Tetrabromobisphenol A showed weak estrogenic activity at 1Â ÃÂ 104Â nM, but significant cytotoxicity above this concentration. The total estradiol equivalency quantities (EEQs) of BPs were in the range of 2.16-49.13Â pg E2Â gâ1 dw, accounting for 0.05-1.47% of the total EEQs in sewage sludge samples. The results indicate that BPs made a minor contribution to the estrogenic activity of the investigated sewage sludge. Nevertheless, our results suggest that considerable attention should be directed to the estrogenic potentials of emerging organic pollutants because of their widespread use and their potential to persist in the environment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemosphere - Volume 124, April 2015, Pages 150-155
Journal: Chemosphere - Volume 124, April 2015, Pages 150-155
نویسندگان
Ting Ruan, Dong Liang, Shanjun Song, Maoyong Song, Hailin Wang, Guibin Jiang,