کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6308945 | 1618857 | 2014 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Fish consumption as a source of human exposure to perfluorinated alkyl substances in Italy: Analysis of two edible fish from Lake Maggiore Fish consumption as a source of human exposure to perfluorinated alkyl substances in Italy: Analysis of two edible fish from Lake Maggiore](/preview/png/6308945.png)
- We analysed PFOS and PFOA in muscle samples of Coregonus lavaretus and Perca fluviatilis.
- PFOS was detected in all 90 samples with concentrations of up to 46.0 ng gâ1 fw.
- PFOA was always under the LOQ (0.50 ng g-1 fw). PFOS levels were not related to fish species, length, or gender.
- PFOS from Lake Maggiore can contribute to the TDI.
- There is a potential risk for the health of consumers with elevated fish intake.
Extensive screening analyses of perfluorooctane sulfonate and related perfluorinated compounds (PFCs) in biota samples from all over the world have identified PFCs as global pollutants and have shown their bioaccumulation into higher trophic levels in the food chain.Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are environmental contaminants belonging to a chemical group known as perfluorinated compounds. PFOS and PFOA are very persistent in the environment and bioaccumulate in humans. They are potential reproductive and developmental toxicants and are considered to be emerging endocrine disrupters.The United States Environmental Protection Agency (USEPA) considers both compounds to be carcinogenic and the European Food Safety Authority (EFSA) recently pointed out that they are associated with adverse health effects. Diet is considered the main source of exposure to PFCs, which have been found more frequently in fish and other seafood, compared to other food groups. In fact, aquatic ecosystems represent the final reservoir for PFCs due to their great affinity for sedimentary and living organic matter. In these systems, measured levels of persistent organic pollutants (POPs) could increase along the trophic web, ultimately affecting humans that consume aquatic species.In this study, PFOS and PFOA was detected by LC-MS/MS in muscle samples of Coregonus lavaretus (European whitefish) and Perca fluviatilis (European perch) collected from Lake Maggiore, a large lake located on the south side of the Italian Alps. PFOA was not found in any of the investigated samples above the limit of quantitation of 0.50 ng gâ1 fresh weight (fw), whereas PFOS was detected in all 90 samples with concentrations of up to 46.0 ng gâ1 fw. Mean concentrations were 22.2 ng gâ1 fw in P. fluviatilis and 20.0 ng gâ1 fw in C. lavaretus.Comparison of our results with literature data on PFOS intake suggested that fish from Lake Maggiore may be a significant source of dietary PFOS exposure, even if the reported values were lower than the Total Daily Intake (TDI) proposed by EFSA.
Journal: Chemosphere - Volume 114, November 2014, Pages 181-186