Cellular effects of metolachlor exposure on human liver (HepG2) cells

► HepG2 cells - immortalized human liver cell line. ► 50 parts per billion metolachlor inhibits growth of HepG2 cells. ► Metolachlor exposure results in reduced cell division rate. ► HepG2 cell cycle progression altered after metolachlor exposure. ► Decrease of cyclin A transcripts after metolachlor exposure in HepG2 cells.