Tributyltin exposure causes lipotoxicity responses in the ovaries of rockfish, Sebastiscus marmoratus

► Lipotoxicity responses of tributyltin in the ovaries of fish were evaluated. ► Tributyltin induced ectopic lipids accumulation in the interstitial of ovaries. ► Tributyltin interfered with testosterone esterification in the ovaries. ► Tributyltin might influence reproductive functions through lipotoxic mechanism.