کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6311677 | 1307556 | 2012 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Derivation of predicted no effect concentrations (PNEC) for 2,4,6-trichlorophenol based on Chinese resident species Derivation of predicted no effect concentrations (PNEC) for 2,4,6-trichlorophenol based on Chinese resident species](/preview/png/6311677.png)
2,4,6-Trichlorophenol (2,4,6-TCP) is a common chemical intermediate and a by-product of water chlorination and combustion processes, and is a priority pollutant of the aquatic environment in many countries. Although information on the toxicity of 2,4,6-TCP is available, there is a lack of information on the predicted no-effect concentration (PNEC) of 2,4,6-TCP, mainly due to the shortage of chronic and site-specific toxicity data. In the present study, acute and sub-chronic toxicity of 2,4,6-TCP on six different resident Chinese aquatic species were determined. PNEC values were calculated and compared by use of two approaches: assessment factor (AF) and species sensitivity distribution (SSD). Values for acute toxicity ranged from 1.1 mg Lâ1 (Plagiognathops microlepis) to 42 mg Lâ1 (Corbicula fluminea) and the sub-chronic no observed effect concentrations (NOECs) ranged from 0.05 mg Lâ1 (Mylopharyngodon piceus) to 2.0 mg Lâ1 (C. fluminea). PNECs obtained by the assessment factor approach with acute (AF = 1000, 0.001 mg Lâ1) or chronic (AF = 10, 0.005 mg Lâ1) toxicity data were one order of magnitude less than those from SSD methods (0.057 mg Lâ1). PNEC values calculated using SSD methods with a 50% certainty for 2,4,6-TCP was less than those obtained by use of the USEPA recommend final chronic value (FCV) method (0.097 mg Lâ1) and the one obtained by use of the USEPA recommend acute-to-chronic (ACR) methods (0.073 mg Lâ1). PNECs derived using AF methods were more protective and conservative than that derived using SSD methods.
⺠Toxicity of 2,4,6-TCP on six resident Chinese aquatic species were determined. ⺠PNECs were calculated using different methods based on resident Chinese species. ⺠PNECs derived using AFs were more conservative than that derived using SSDs. ⺠A PNEC of 0.057 mg Lâ1 was recommended for Chinese aquatic ecosystem protection.
Journal: Chemosphere - Volume 86, Issue 1, January 2012, Pages 17-23