کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6332928 | 1619798 | 2013 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Essential and toxic element concentrations in blood and urine and their associations with diet: Results from a Norwegian population study including high-consumers of seafood and game
ترجمه فارسی عنوان
غلظت عناصر ضروری و سمی در خون و ادرار و ارتباط آنها با رژیم غذایی: نتایج مطالعات جمعیت نروژی شامل مصرف کنندگان بالا غذاهای دریایی و بازی
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کلمات کلیدی
BMDLJECFAPCBNNRBMDEFSAFFQArsenic - آرسنیکPersistent organic pollutants - آلایندههای آلی دیرپا(پایدار)European Food Safety Authority - اداره ایمنی اروپاPolychlorinated biphenyl - بیفنیل پلی کربناتMercury - جیوهbenchmark dose - دوز معادلLead - سربbody mass index - شاخص توده بدنBMI - شاخص توده بدنیJoint FAO/WHO Expert Committee on Food Additives - مجمع متخصص FAO / WHO در مورد مواد افزودنی مواد غذاییPTWI - موقت مصرف هفتگی قابل تحملProvisional Tolerable Weekly Intake - هزاره تحویل موقتpop - پاپFFQ, Food Frequency Questionnaire - پرسشنامه بسامد خوراک، پرسشنامه بسامد مصرف غذاییCadmium - کادمیمIodine - ید
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
چکیده انگلیسی
The first aim of the study was to evaluate calculated dietary intake and concentrations measured in blood or urine of essential and toxic elements in relation to nutritional and toxicological reference values. The second aim was to identify patterns of the element concentrations in blood and urine and to identify possible dietary determinants of the concentrations of these elements. Adults with a known high consumption of environmental contaminants (n = 111), and a random sample of controls (n = 76) answered a validated food frequency questionnaire (FFQ). Complete data on biological measures were available for 179 individuals. Blood and urine samples were analyzed for selenium, iodine, arsenic, mercury, cadmium and lead. Principal component analysis was used to identify underlying patterns of correlated blood and urine concentrations. The calculated intakes of selenium, iodine, inorganic arsenic and mercury were within guideline levels. For cadmium 24% of the high consumer group and 8% of the control group had intakes above the tolerable weekly intake. Concentrations of lead in blood exceeded the bench-mark dose lower confidence limits for some participants. However, overall, the examined exposures did not give rise to nutritional or toxicological concerns. Game consumption was associated with lead in blood (Bln 0.021; 95%CI:0.010, 0.031) and wine consumption. Seafood consumption was associated with urinary cadmium in non-smokers (Bln 0.009; 95%CI:0.003, 0.015). A novel finding was a distinct pattern of positively associated biological markers, comprising iodine, selenium, arsenic and mercury (eigenvalue 3.8), reflecting seafood intake (B 0.007; 95%CI:0.004, 0.010). The study clearly demonstrates the significance of seafood as a source of both essential nutrients and toxic elements simultaneously and shows that exposure to various essential and toxic elements can be intertwined.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Science of The Total Environment - Volumes 463â464, 1 October 2013, Pages 836-844
Journal: Science of The Total Environment - Volumes 463â464, 1 October 2013, Pages 836-844
نویسندگان
B.E. Birgisdottir, H.K. Knutsen, M. Haugen, I.M. Gjelstad, M.T.S. Jenssen, D.G. Ellingsen, Y. Thomassen, J. Alexander, H.M. Meltzer, A.L. Brantsæter,