کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6371868 | 1624009 | 2016 | 10 صفحه PDF | دانلود رایگان |
- We present 3D IBM for the simulation of cell growth and cytokinesis.
- A surface remeshing algorithm is applied to prevent the mesh distortion.
- To keep the cell volume during cytokinesis, we use a volume-conserving algorithm.
In this paper, we present a three-dimensional immersed boundary method to simulate the eukaryotic cell growth and cytokinesis. The proposed model and numerical method are a non-trivial three-dimensional extension of the previous work (Li et al., 2012). Unstructured triangular meshes are employed to discretize the cell membrane. The nodes of the surface mesh constitute a set of Lagrangian control points used to track the motion of the cell. A surface remeshing algorithm is applied to prevent mesh distortion during evolution. We also use a volume-conserving algorithm to maintain the mass of cells in cytokinesis. The ability of the proposed method to simulate cell growth and division processes is numerically demonstrated.
Journal: Mathematical Biosciences - Volume 271, January 2016, Pages 118-127