کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6391895 1628422 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of sub-lethal concentrations of biocides on the susceptibility to antibiotics of multi-drug resistant Salmonella enterica strains
ترجمه فارسی عنوان
تاثیر غلظت های زیر بیهوشی بیوسیدها بر حساسیت به آنتی بیوتیکی سویه های مقاوم به چند داروی سالمونلا ادراری
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
چکیده انگلیسی


- Ten Salmonella strains were exposed to sub-inhibitory concentrations of biocides.
- The MIC of sodium nitrite and sodium hypochlorite increased after exposure.
- The cultures exposed to biocides showed reduced susceptibility to antibiotics.
- The susceptibility to aminoglycosides and cephalosporins was strongly affected.
- The impact of exposure on susceptibility to antibiotics was dependent on the strain.

Ten multi-drug resistant Salmonella enterica isolates belonging to ten different serotypes were exposed to increasing sub-inhibitory concentrations of three biocides widely used in food industry facilities (trisodium phosphate, sodium nitrite, or sodium hypochlorite). Cultures were tested, before and after exposure to biocides, against 31 antibiotics of clinical significance by means of a standard disk-diffusion technique (CLSI). Exposed cultures displayed reduced susceptibility to a range of antibiotics, as compared with not exposed cultures. The impact of biocide exposure on reduced susceptibility to antibiotics was dependent on the Salmonella strain and the antibiotic family tested, susceptibility to aminoglycosides and cephalosporins being the most strongly affected. Results in the present study suggest that extensive use of biocides at sub-lethal concentrations could contribute to the emergence of antibiotic resistance in multi-drug resistant Salmonella enterica strains and therefore represent a public health risk. The intra-specific differences observed in antibiotic susceptibility underline the need to screen a wide range of strains.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Control - Volume 40, June 2014, Pages 329-334
نویسندگان
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