کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6472785 1424140 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel platform based on defect-rich knotted graphene nanotubes for detection of small biomolecules
ترجمه فارسی عنوان
یک پلت فرم جدید مبتنی بر نانولوله های گرافنی پیچ خورده غنی از نقص برای تشخیص زیست مولکول های کوچک است
کلمات کلیدی
نانولوله های گرافنی گره خورده، نقص ساختاری، بیومولکول های کوچک، احساس
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
چکیده انگلیسی


- Curvature of the SC-CNTs' cavities had more local pressure, leading to form k-GNTs.
- k-GNTs are divided into sections by knots with abundant edge-plane sites/defects.
- k-GNTs exhibited excellent catalytic activity, sensitivity and reproducibility.

Detection of disease-related small biomolecules was of great significance for clinical diagnostics and treatment. In this work, we synthesized defect-rich knotted graphene nanotubes (k-GNTs) via chemical oxidative etching of stacked-up carbon nanotubes (SC-CNTs) followed by chemical reduction, to detect disease-related small biomolecules. We further studied the electrochemical properties using three representative redox probes and analyzed their biosensitivity using five biomolecules. The k-GNT-modified electrodes exhibited excellent electrochemical response, with the lowest ΔEp and the highest k0. Besides, the modified electrodes could simultaneously detect and discriminate between dopamine (DA), ascorbic acid and uric acid (UA), as well as differentiate phenethylamine (PEA) and epinephrine (EP) existed in newborn rat serum, providing the wide linear detection ranges with high sensitivities for DA, UA, PEA, and EP. These excellent electrocatalytic properties could be ascribe to the unique knotted graphene nanotube structure with high proportion of defect/edge sites, large, accessible, three-dimensional, accessible surface area, fewer oxygen-containing groups and doped N atoms. Our work reveals defect-rich k-GNTs as a promising platform for further applications in electrochemical biosensing and electrocatalysis.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Electrochimica Acta - Volume 217, 1 November 2016, Pages 47-54
نویسندگان
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