Structural characterization of thermostable, solvent tolerant, cytosafe tannase from Bacillus subtilis PAB2

- Tamarind seed can be successfully used as cheap substrate for tannase production.
- Bacillus subtilis PAB2 yields a 52 kDa tannase with globular secondary structure.
- Tannase exhibits stability at a wide range of temperature, salt and organic solvent.
- Native conformation of tannase alike a spherical nanoparticle.
- Tannase have no cytotoxicity on Vero cell line and rat model.