Analysis of sequence repeats of proteins in the PDB

- PDB-wide analysis of sequence repeats in a non-redundant set of proteins.
- Use of different bioinformatics tools such as RADAR, PDBeFOLD, PDBsum and Pfam to identify and characterize the sequence repeats in a protein.
- Sequence identity of the repeats falls in the range of 20-40% and, their superimposed structures of the sequence repeats maintain similar overall folding.
- Sequence repeats are involved in the function of the protein through functionally important residues in the repeat regions.
- Sequence repeats in the domains of the proteins show that repeats involved in the function of protein possess conserved sequence motifs.