Chitosan/β-1,3-glucan/calcium phosphate ceramics composites-Novel cell scaffolds for bone tissue engineering application

Our results demonstrated that novel composites possess good compressive strength as the effect of polysaccharide components of scaffolds, are very elastic, are non-toxic, favourable to cell adhesion and promote cell proliferation. However, novel biomaterials revealed relatively low Young's modulus values. Thus, we infer that fabricated novel composites are promising materials for bone tissue engineering application as cell scaffolds to fill small bone losses rather than as massive bone fillers exposed to mechanical load.