Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from l-tyrosine

- The polyphenolic compound resveratrol was produced from l-tyrosine in Escherichia coli.
- A multivariate modular metabolic strategy was employed to balance the overall pathway for resveratrol production.
- Current fermentation strategies relying on two separate step culture protocols were developed for using a single medium to perform resveratrol production.