1,3-Propanediol production and tolerance of a halophilic fermentative bacterium, Halanaerobium saccharolyticum subsp. saccharolyticum

► Halanaerobium saccharolyticum ferments glycerol to 1,3-propanediol. ► 1,3-Propanediol production is vitamin B12 dependent. ► Only 64 μg/l vitamin B12 is enough to produce maximally 1,3-propanediol and biomass. ► 1,3-Propanediol causes growth inhibition.