Reusability of ADH and GDH producing Arxula adeninivorans cells and cell extract for the production of 1-(S)-phenylethanol

- Synthesis of 1-(S)-phenylethanol by calcium alginate immobilized crude extract,
- Triton X-100 permeabilized cells and permeabilized and immobilized cells co-expressing BmGDH and RrADH in Arxula adeninivorans.
- Highest process stability for permeabilized and immobilized cells with 53 reaction cycles.
- 5 reaction cycles gave 410.7 mg/20 mL 1-(S)-phenylethanol (optical purity: 94.8 ± 0.07%, ee of ≥99%).