Copper(II) SBA-15: A reusable catalyst for azide–alkyne cycloaddition

• Copper(II) catalyses the alkyne–alcyne cycloaddition reaction.
• Cu-SBA-15 operates by a copper(I)-like mechanism leading complete regioselectivity.
• The catalyst can be reused without loss of yield and regioselectivity.

The azide–alkyne cycloaddition reaction was investigated under catalytic conditions involving a copper(II) loaded silica based mesoporous material. Cu(II) SBA-15 demonstrated a high catalytic effect in 1,4-triazoles synthesis in organic. No additives such as a base or a reductant are required. Quantitative yields were obtained and a mere filtration of the mesoporous material which retains copper(II) allows the recovery of the catalyst. In addition, up to 5 times recycling of the catalyst was achieved without loss of the activity affording 1,4-triazoles in a yield up to 98%.

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