کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6553712 160896 2015 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Population data of the GlobalFiler® Express loci in South Portuguese population
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
Population data of the GlobalFiler® Express loci in South Portuguese population
چکیده انگلیسی
Allele frequencies and other relevant forensic parameters for 21 loci studied with GlobalFiler® Express amplification kit (Life Technologies) were calculated in a population of individuals residing in the south of Portugal. Blood stain samples were obtained from a total of 502 unrelated individuals involved in paternity testing casework and directly PCR amplified with GlobalFiler® Express following manufacturer's instructions. This kit comprises all the loci included in the extended European Standard Set (ESS) and in the Combined DNA Index System (CODIS), besides the very polymorphic D2S441, D19S433, and SE33. In our laboratory this is used as a screening tool to solve complex cases, as fatherless paternity tests or to help in paternity investigations where there is the need to study additional genetic markers. These studies are necessary to calculate statistical forensic parameters, such as power of discrimination or as power of exclusion. Statistical parameters including heterozigosity, homozigosity and combined power of exclusion were estimated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Forensic Science International: Genetics - Volume 19, November 2015, Pages 39-41
نویسندگان
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