کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6554074 | 160898 | 2014 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
An illustration of the effect of various sources of uncertainty on DNA likelihood ratio calculations
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
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چکیده انگلیسی
Population database sampling uncertainty represents only one of the sources of uncertainty that affects estimation of the strength of DNA evidence. There are other uncertainties which can potentially have a much larger effect on the statistic such as, those inherent in the value of Fst, the weights given to genotype combinations in a continuous interpretation model, and the composition of the relevant population. In this paper we model the effect of each of these sources of uncertainty on a likelihood ratio (LR) calculation and demonstrate how changes in the distribution of these parameters affect the reported value. In addition, we illustrate the impact the different approaches of accounting for sampling uncertainties has on the LR for a four person mixture.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Forensic Science International: Genetics - Volume 11, July 2014, Pages 56-63
Journal: Forensic Science International: Genetics - Volume 11, July 2014, Pages 56-63
نویسندگان
D. Taylor, J-A. Bright, J. Buckleton, J. Curran,