کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6824971 548471 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Frontal cortex control dysfunction related to long-term suicide risk in recent-onset schizophrenia
ترجمه فارسی عنوان
اختلال کنترل قشر مغزی در ارتباط با خطر درازمدت خودکشی در ابتلا به اسکیزوفرنیا
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی
This study provides unique evidence that suicide risk directly relates to PFC-based circuit dysfunction during goal-representation, in a major mental illness with significant suicide rates. Among those with suicidal ideation, the overt expression in suicidal behavior may stem from impairments in premotor cortex support of action-planning as an expression of control. Further work should address how PFC-based control function changes with risk over time, whether this brain-behavior relationship is specific to schizophrenia, and address its potential utility as a biomarker for interventions to mitigate suicide risk.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Schizophrenia Research - Volume 157, Issues 1–3, August 2014, Pages 19-25
نویسندگان
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