Rates and predictors of remission in first-episode schizophrenia within 1Â year of antipsychotic maintenance treatment. Results of a randomized controlled trial within the German Research Network on Schizophrenia

By far most of the first-episode patients reached a temporary state of full symptomatic remission within 1 year of antipsychotic treatment. However, only about 50% achieved sustained, enduring remission. Negative symptoms are still a major treatment obstacle to enduring remission in schizophrenia.