کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6826015 | 548513 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cannabis use, cognition and brain structure in first-episode psychosis
ترجمه فارسی عنوان
استفاده از کانابیس، شناختی و ساختار مغز در روانشناسی اولین مرحله
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
چکیده انگلیسی
Cannabis use is highly prevalent worldwide and it is associated with psychosis, but its effects on brain structure and cognition are still controversial. The aim of this paper is to investigate cognitive functioning and brain structure in patients with their first episode of psychosis who used Cannabis. We examined gray matter and lateral ventricle volumes in 28 patients with first-episode psychosis and a history of Cannabis use, 78 patients without a history of Cannabis use and 80 healthy controls who had not used Cannabis. Cognition was assessed using forward and backwards digit span tests, from the Wechsler Memory Scale-Third Edition (WMS-III) and the Controlled Oral Word Association Test (COWAT). Patients with a history of Cannabis use had less brain abnormalities, characterized by gray matter and lateral ventricle volume preservation, as well as less attentional and executive impairments compared to patients without a history of Cannabis use. Cannabis-using patients who develop psychosis have less neurodevelopmental impairment and better cognitive reserve than other psychotic patients; perhaps reflecting different etiological processes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Schizophrenia Research - Volume 147, Issues 2â3, July 2013, Pages 209-215
Journal: Schizophrenia Research - Volume 147, Issues 2â3, July 2013, Pages 209-215
نویسندگان
Paulo Jannuzzi Cunha, Pedro Gomes P. Rosa, Adriana de Mello Ayres, Fábio L.S. Duran, Luciana C. Santos, Marcia Scazufca, Paulo R. Menezes, Bernardo dos Santos, Robin M. Murray, José Alexandre S. Crippa, Geraldo F. Busatto, Maristela S. Schaufelberger,