Highly efficient and stable palladium/imidazolium salt-phosphine catalysts for Suzuki–Miyaura cross-coupling of aryl bromides

A robust palladium catalyst system supported by the hybrid ligand N-heterocyclic carbene along with a phosphine derived from ferrocene has been discovered for the Suzuki cross-coupling reaction. This novel system effectively catalyzes the cross-coupling of aryl bromides and phenylboronic acid with up to 20,000 TONs and 10,000 h−1 TOFs to produce biaryl products in excellent yields.

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