کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
68752 48522 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Alkoxy group facilitated ring closing metathesis (RCM) of acyclic 1,6-dienes: Facile synthesis of non-racemic highly substituted cyclopentenols
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی کاتالیزور
پیش نمایش صفحه اول مقاله
Alkoxy group facilitated ring closing metathesis (RCM) of acyclic 1,6-dienes: Facile synthesis of non-racemic highly substituted cyclopentenols
چکیده انگلیسی

Alkoxymethyl groups at the C-5 allylic position of 1,6-dienols have been found to accelerate RCM reaction significantly with the Grubbs’ catalyst PhCHRu(PCy3)2Cl2 over those of 1,6-dienols containing alkyl or hydroxymethyl groups. This phenomenon has been used for direct access to 4-silyloxymethyl and 4,6-bis(silyloxymethyl) cyclopentenols, potential intermediates to the synthesis of carbasugars and the carbocyclic nucleosides carbovir, abacavir and BCA.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Catalysis A: Chemical - Volume 254, Issues 1–2, 19 July 2006, Pages 85–92
نویسندگان
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