Synthesis of poly(ethylene glycol) (PEG) grafted silica nanoparticles with a minimum adhesion of proteins via one-pot one-step method

- Fabricated silica NPs by Stober method were grafted by poly(ethylene glycol).
- Silica core-PEG shell nanoparticles were successfully synthesized.
- The impact of PEG, TEOS NH4OH concentrations on the NPs size was investigated.
- The affinity between modified NPs and protein was remarkably reduced.