PEGylation of surfacted magnetite core-shell nanoparticles for biomedical application

- The mechanisms of oleate adsorption on as-synthesized and purified MNPs are different.
- PEG adsorption increases the weight of steric component in electrosteric stabilization by oleate.
- MNPs become clustered upon OA adsorption; cluster size is larger for as-synthesized MNPs.
- PEG-surfacted MNPs do not show cytotoxicity and hemolytic potential on human blood.
- MRI T2 enhancement of as-synthesized MNPs supports higher degree of clustering.