Influence of temperature, anions and size distribution on the zeta potential of DMPC, DPPC and DMPE lipid vesicles

- Liposomes composed of neutral lipids exhibit non-zero zeta potentials.
- Zeta potentials of liposomes in water were different from those in ionic medium.
- The sign of the zeta potential varies with the kind of lipid, medium, phase state and lamellarity.
- The orientation of the head group in the liposome is relevant in the sign of the zeta potential.